Urea Cycle : Definition, Function, Reaction And Diagnosis





Urea cycle

The Urea Cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2) 2CO from ammonia (NH3). This cycle occurs in ureotelic organisms. The urea cycle converts highly toxic ammonia into urea for immersion. This cycle was the first metabolic cycle to be discovered, five years ago by the discovery of the TCA cycle (Hans Krebs and Kurt Henseleit, 1932). The urea cycle is primarily in the liver and in the kidney, to some degree.
In humans and mammals, approximately 80% of nitrogen is produced in the form of urea emitted, which is produced through a series of reactions in cytosol and mitochondrial matrix of liver cells. These reactions are collectively called the urea cycle or the Krebs-Hensleit cycle. Read More


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